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According to reports, every 30 s in the world, one diabetic patient suffers from amputation due to persistent diabetic chronic ulcers, and the annual cost of medical costs and lots of productivity due to diabetic wounds is more than 200 billion US dollars (Al-Mohaithef et al., 2022)

Plasma homocysteine levels correlated to interactions between folate status and methylene tetrahydrofolate reductase gene mutation in women with unexplained recurrent pregnancy loss

Disulfide linkers exploit the high level of intracellular reduced glutathione to release free drug inside the cell

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